One-Pot Cajun Chicken Alfredo

Featured in: Quick Comfort Meals

This creamy Cajun chicken Alfredo features tender diced chicken simmered with orzo pasta in a rich, zesty sauce. Combining spices like Cajun seasoning, smoked paprika, and red pepper flakes, this one-pot meal balances savory richness with a touch of heat. Aromatic onion and garlic build the base, while heavy cream and Parmesan melt into a silky sauce. Quick to prepare and ideal for weeknight dinners, this dish offers a comforting yet vibrant flavor in every bite. Garnished with fresh parsley, it pairs perfectly with crusty bread or a light salad.

Updated on Sun, 23 Nov 2025 16:47:00 GMT
Creamy One-Pot Cajun Chicken Alfredo Orzo features tender chicken and zesty sauce, perfect for a flavorful dinner. Save
Creamy One-Pot Cajun Chicken Alfredo Orzo features tender chicken and zesty sauce, perfect for a flavorful dinner. | freshyforks.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This recipe has become a favorite for quick weeknight dinners that don’t sacrifice flavor or comfort.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), Salt and black pepper, to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion, chopped (yellow or sweet preferred), 3 cloves garlic, minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese, freshly grated
  • Garnish: 1 tbsp fresh parsley, chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium high heat. Add diced chicken, season with salt and pepper, and sear for 3 4 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 2 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 1 2 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 12 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
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This recipe always brings the family together around the table for a cozy and flavorful meal.

Notes

For a lighter dish, use half and half instead of heavy cream and reduce the cheese slightly. Add bell peppers or spinach for extra vegetables and color. Serve with crusty bread or a green salad. Pairs well with a chilled Sauvignon Blanc or light lager.

Required Tools

Large skillet with lid, Wooden spoon or spatula, Chefs knife, Cutting board, Measuring cups and spoons, Grater (for Parmesan)

Allergen Information

Contains dairy (butter, cream, Parmesan cheese) and gluten (orzo pasta). May contain traces of other allergens always check ingredient labels if sensitivity is a concern.

This photo depicts a comforting bowl of One-Pot Cajun Chicken Alfredo Orzo, ready to serve with fresh parsley. Save
This photo depicts a comforting bowl of One-Pot Cajun Chicken Alfredo Orzo, ready to serve with fresh parsley. | freshyforks.com

This dish perfectly balances quick preparation with bold, comforting flavors every time.

Recipe Questions & Answers

Can I substitute the chicken with other proteins?

Yes, shrimp or Andouille sausage work great as alternatives. Adjust cooking times accordingly to prevent overcooking.

How do I make the dish less spicy?

Reduce or omit the red pepper flakes and use milder Cajun seasoning to control the heat level to your preference.

What pasta can I use instead of orzo?

Small pasta like acini di pepe or Israeli couscous can be used as substitutes, cooking times may vary slightly.

Is there a lighter option for the creamy sauce?

Using half and half instead of heavy cream along with slightly less Parmesan cheese will lighten the sauce while keeping creaminess.

Can I add vegetables to the dish?

Absolutely, bell peppers, spinach, or other quick-cooking veggies can be incorporated for added color and nutrition.

One-Pot Cajun Chicken Alfredo

A creamy Cajun chicken and orzo dish featuring bold spices and smooth Alfredo sauce ready in 30 minutes.

Prep time
10 minutes
Time to cook
20 minutes
Time required
30 minutes
Recipe by Freshyforks Lena Brooks


Skill level Easy

Cuisine Cajun

Portions 4 Number of servings

Diet Details None specified

What You'll Need

Chicken

01 1 lb diced chicken breast
02 Salt to taste
03 Black pepper to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp butter
03 1 medium chopped onion
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tbsp fresh parsley, chopped

Directions

Step 01

Sear the chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season diced chicken with salt and pepper, then sear for 3 to 4 minutes until golden brown. Remove and set aside.

Step 02

Sauté aromatics: In the same skillet, add chopped onion and sauté for 2 to 3 minutes until translucent. Add minced garlic and cook for 1 minute until fragrant.

Step 03

Toast the orzo: Add orzo pasta to the skillet and stir to combine. Toast for 1 to 2 minutes until lightly golden.

Step 04

Simmer with spices and broth: Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and most liquid is absorbed.

Step 05

Incorporate cream and cheese: Remove from heat and gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.

Step 06

Combine chicken and finish cooking: Return cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Adjust seasoning to taste.

Step 07

Garnish and serve: Sprinkle chopped fresh parsley over the dish before serving.

Tools Needed

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons
  • Grater

Allergy info

Review ingredients for allergens. Reach out to medical experts if you're not sure.
  • Contains dairy and gluten; verify ingredient labels for other allergens

Nutritional breakdown (each serving)

This nutritional data guides only—don't treat as medical advice.
  • Energy (Calories): 560
  • Lipids: 28 grams
  • Carbohydrates: 45 grams
  • Proteins: 35 grams